We at abberior love donuts

Stefan Hell overcame Abbe’s diffraction limit in light microscopy with the help of a donut-shaped laser beam. Since then, the donut has been abberior’s best friend. In STED, it de-excites fluorophores and increases resolution, providing us with exciting superresolution images. Even when resolution took another quantum leap with MINFLUX, we could rely on our good

Watch recording: Webinar on MINFLUX tracking

Webinar on MINFLUX tracking. Jan. 17, 2024, 15:30 CET

with unprecedented spatio-temporal resolution!

More space for Nobel-awarded microscopy technique – abberior moves into new headquarters

abberior's new headquarters in Göttingen, Germany

Twelve years after abberior’s foundation we are finally there: We moved into our brand-new headquarters in Hans-Adolf-Krebs Weg 6 at the North Campus of the University of Göttingen! “The move reflects our strong growth since the company’s foundation,” says abberior CEO Dr. Gerald Donnert. ” Our team now comprises more than 130 colleagues – many

RAYSHAPE your image!

Dynamic aberration correction with a deformable mirror, only from abberior

Bye, bye, bleaching! Start “endless“ live-cell imaging with our NEW exchangeable HaloX® labels!

Bye, bye, bleaching! Start „endless“ live- cell imaging with our NEW exchangeable HaloX labels!

Live-cell fluorescence microscopy suffers from the limited number of commercially available live dyes as each target requires its specific reactive group. The recent development of genetically encoded self-labeling protein tags such as the HaloTag® overcomes this limitation and offers more flexibility to live-cell applications. However, the covalent, irreversible attachment of the HaloTag® labels to the

MINFLUX unravels the structural dynamics of PIEZO1 ion channels

MINFLUX unravels the structural dynamics of PIEZO1 ion channels in living cells

New study shows microscopy technique’s potential

Why do superresolution microscopists love alpacas?

Immunofluorescence staining with alpaca nanobodies

Check out our latest articles about immunofluorescence labeling with antibodies and nanobodies. “Why do superresolution microscopists love alpacas?” It is a very simple yet very important fact: the localization precision of any microscope can only be as good as the size of the label allows. Read article > “Let the cells shine with immunofluorescence labeling!”

abberior MINFLUX microscope measures distances with Angström precision

MINFLUX measures (B) the orientation and the distance of two fluorophores attached to well-defined binding sites of the protein dimer PASc (A).

Researchers in Göttingen, Heidelberg and Berlin used a MINFLUX instrument from abberior to monitor the relative position of two fluorophores simultaneously, with sub-nanometer precision. Since these fluorophores were attached to well-defined sites on small proteins and oligomers, this provides direct access to the confirmation and orientation of these macromolecules. In one experiment, Hell and colleagues

Interview with Stefan Hell about kinesin tracking with MINFLUX (English translation)

Tracking of the motion of the motor protein kinesin-1 with MINFLUX

Translation of the article “Was nie ein Mensch zuvor gesehen hat” in LaborJournal JOURNAL CLUB What no human being has ever seen before The developers of super-resolution fluorescence microscopy were awarded the 2014 Nobel Prize in Chemistry by the Royal Swedish Academy. With MINFLUX, prize winner Stefan Hell has since improved its resolving power by

Article in Technology Review on the current boom of light microscopy

Das ist ein Mikroskop

Light microscopy is booming. Optical tricks make single proteins in cells visible and allow to observe complete organs. Now smart microscopes emerge which adjust to living tissue in no time – and watch the brain thinking. „MINFLUX und MINSTED do not only see ten times smaller details, they also require a hundred times less fluorescence

abberior runs…

abberior team at the Göttingen Altstadtlauf 2023

@ Göttinger Altstadtlauf 2023

Article and interview with Stefan Hell about kinesin tracking with MINFLUX’ latest technical developments

Was nie ein Mensch zuvor gesehen hat

What no human being has seen before

Technology feature in Nature about MINFLUX and tracking kinesin

„MINFLUX is capable of tracking kinesin even amid the bustle of living cells.” Powerful microscope captures motor proteins in unprecedented detail. Nature, June 8, 2023 “[with MINFLUX] … they are able to track kinesin very precisely. And when you have a live cell system, that’s even more spectacular.” Michelle Digman, University of California Powerful microscope

Hip hip hurray! Our brand new nanobody conjugated abberior STAR dyes are out now.

Nanobody conjugated abberior STAR dyes webinar

Watch the webinar recording “Nanobodies for superresolution microscopy”

Article in Physics Today about MINFLUX and tracking kinesin.

“But it (MINFLUX) was also well suited, for the first time, for tracking single fluorophores with simultaneous nanometer and millisecond precision.” Physics Today 76 (5), 14 (2023) Read the full article with Nobel Laureate Stefan W. Hell and Jonas Ries of the EMBL in Physics Today > More information about MINFLUX and “How the donut

English version of the Spektrum interview with Nobel Laureate Stefan W. Hell about STED, MINFLUX and PALM/STORM.

"If I want to study movement in a living cell or in an artificial system, MINFLUX allows me to see the movement of fluorescent molecules attached to something 100 times faster - with the same accuracy." An interview with Nobel Laureate Stefan W. Hell about STED, MINFLUX and PALM/STORM.

Translation of the article “Ein Potenzial, das noch in keiner Form gehoben ist” in the popular science journal Spektrum.de > MICROSCOPY A potential that has yet to be tapped into In 2014, Stefan Hell shared the Nobel Prize in Chemistry for developing STED microscopy. Building on STED, he has now devised a revolutionary new fluorescence

Observe motor proteins stepping along in living cells with MINFLUX

For the first time, the precise motion of the motor protein kinesin-1 as it walks on microtubules in living cells was measured by researchers from abberior, the European Molecular Biology Laboratory (EMBL), and Utrecht University. Kinesin belongs to a class of motor proteins that transport large cargo to their required destinations in the cell. It can

Lecture by Nobel Laureate Stefan W. Hell on his MINFLUX concept.

Nobel laureate Stefan W. Hell gives a lecture on his MINFLUX concept.

MINFLUX allows an everyday 3D resolution of 2 – 3 nm and offers about 100 times faster tracking than with a camera-based system. Don’t miss this chance to listen to the inventor of STED and MINFLUX. Watch the full video >

Spektrum interview with Nobel Laureate Stefan W. Hell about STED, MINFLUX and PALM/STORM.

"If I want to study movement in a living cell or in an artificial system, MINFLUX allows me to see the movement of fluorescent molecules attached to something 100 times faster - with the same accuracy." An interview with Nobel Laureate Stefan W. Hell about STED, MINFLUX and PALM/STORM.

“If I want to study movement in a living cell or in an artificial system, MINFLUX allows me to see the movement of fluorescent molecules attached to something 100 times faster – with the same accuracy.” Read the full interview with Nobel Laureate Stefan W. Hell in Spektrum > More information about MINFLUX and “How

NEW abberior LIVE ORANGE mito – a probe for cristae structure in living mitochondria!

abberior LIVE ORANGE mito is a new bright fluorescent probe that stains the structure of cristae in living mitochondria. Simply place the probe on your sample and immediately study the beauty of mitochondrial movement. Due to the special design of the probe, repeated excitation over a long period of time is possible without toxic effects

Save up to 25 % with abberior DYES DELUXE packages

With abberior‘s DYES DELUXE packages you'll save up to 25%

With our DYES DELUXE packages, you can easily refresh your stock of labeled antibodies on demand!

Watch Recording: Live-cell imaging – nanometer-sized fluorescent probes and tags

LIVE-CELL imaging with nanometer probes and tags. Get the video of the online symposium.

Has the Nobel Prize for Click Chemistry sparked your interest in using click chemistry for your imaging experiments? Learn more about in this webinar: “Live-cell imaging with nanometer probes and tags”. With the advancement of superresolution microscopy techniques such as STED or MINFLUX, the size of the label plays an increasingly important role. The clickable system

abberior rocked @ EMBL – Imaging down to single-molecule resolution: STED and MINFLUX nanoscopy

Impressions from abberior's course at EMBL from 19/09 to 24/09/2022: tissue imaging with FACILITY

Impressions from the course, September 19. – 24.

New Publication: Two-color live-cell STED nanoscopy by click labeling with cell-permeable fluorophores

Two-color live-cell STED with click labeling, movie with 60 Frames

We demonstrate two-color STED imaging of living cells using various pairs of dyes. To this end, we combine click-chemistry-based protein labeling with other orthogonal and highly specific labeling methods, enabling long-term STED imaging of different target structures in living specimens. Publication Carola Gregor, et al.: “Two-color live-cell STED nanoscopy by click labeling with cell-permeable fluorophores”, bioRxiv (2022)

Wirtschafts Woche selects Germany’s most innovative SMEs.

WirtschaftsWoche places abberior among the 100 most innovative SMEs in Germany

abberior among the best 100!

abberior at MAF 2022 in Gothenburg

Meet us and our STEDYCON at MAF 2022 in Gothenburg, Sweden and we'll image your sample on site – LIVE

Visit us and we’ll image your sample – LIVE, September 11. – 14.

Stefan Hell is admitted to the Order Pour le mérite

The admission is one of the highest honors for scientists and artists in Germany.

Tracking of biomolecules: MINFLUX at its best!

MINFLUX now changes the game of protein tracking. Two independent publications on MINFLUX tracking of motor proteins kinesines moving along microtubules.

Would you like to learn more about cutting edge tracking?

Molecular map of the synapse

3D MINFLUX image of protein bassoon in rod photoreceptor synapses prepared using Heat Assisted Rapid Dehydration (HARD). The z-coordinate is color-coded to highlight the two parallel rows of molecules surrounding the active site.

Scientists at the Institute for Auditory Neuroscience, UMG and abberior instruments have made fascinating discoveries about molecular organization in the active zone of rod photoreceptor cells.

Let’s run together!

abberior team on fire at 32. Goettinger Altstadtlauf 2022

abberior team at 32. Göttinger Altstadtlauf