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FLEXPOSURE special
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MATRIX special
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The price of a STED microscope
Today’s research microscopes are increasingly powerful, modular, and combinatorial. There’s a lot of options out there. While the price is unquestionably a deal-breaker for purchase, a more helpful criterion is value.
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Missense mutations in the central domains of cardiac Myosin binding protein-C and their potential contribution to hypertrophic cardiomyopathy
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RAYSHAPE special
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Bye, bye, bleaching! Start “endless“ live-cell imaging with our NEW exchangeable HaloX® labels!
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abberior LIVE HaloX
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Why do superresolution microscopists love alpacas?
It is a very simple yet very important fact: the localization precision of any superresolution microscope can only be as good as the size of the fluorescent staining allows. In other words, when your fluorescent dye is too big or too far away from the protein you want to label, you will never be able to reach a resolution that is higher than this offset. The good news is: there are ways to reduce the offset between target protein and fluorescent label. And one of these are nanobodies.
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STED and virology
A little insight into the advances in virus research made possible by STED microscopy and a hint to were the journey might go.
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STED-PAINT for high-perfomance superresolution
The combination of STED microscopy and PAINT circumvents the physical limitations of current labeling technology.
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Labeling for STED microscopy
For STED microscopy, similar sample preparation techniques may be utilized as for conventional microscopy. However, the increase in special resolution requires additional precautions to ensure the structural preservation of the specimen.
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Article in Technology Review on the current boom of light microscopy
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Superresolution for biology: when size, time, and context matter
The spatial resolution achievable with today’s light microscopes has unveiled life at the scale of individual molecules. Size is no longer a barrier to seeing biology at the most fundamental level. But life is not static. It emerges from movement and change. How do superresolution technologies hold up to the challenges of documenting dynamic biological mechanisms?
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Career
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abberior STAR nanobody
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A Bright Surprise: Live‐Cell Labeling with Negatively Charged Fluorescent Probes based on Disulfonated Rhodamines and HaloTag
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abberior special
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abberior LIVE special
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abberior STAR special
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Actin cytoskeleton and complex cell architecture in an Asgard archaeon
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How PSF width and photon number impact resolution
Photon numbers from the emitting fluorophore. Width of the PSF. How do they impact the resolution of a microscope? Here’s a simple graphic that lays out those effects.
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Watch Recording: Live-cell imaging – nanometer-sized fluorescent probes and tags
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Wirtschafts Woche selects Germany's most innovative SMEs.
abberior among the best 100!
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Two-photon, fiber-coupled, super-resolution microscope for biological imaging
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Draft Sequencing Crested Wheatgrass Chromosomes Identified Evolutionary Structural Changes and Genes and Facilitated the Development of SSR Markers
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Reduced growth rate of aged muscle stem cells is associated with impaired mechanosensitivity
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LSSmScarlet, dCyRFP2s, dCyOFP2s and CRISPRed2s, Genetically Encoded Red Fluorescent Proteins with a Large Stokes Shift
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Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium
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Two-colour live-cell nanoscale imaging of intracellular targets
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Carborhodol: a new hybrid fluorophore obtained by combination of fluorescein and carbopyronine dye cores
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