Abberior offers different embedding media. Abberior Mount embedding media are aqueous embedding media with a refractive index in the range of 1.38. They are very convenient in terms of application. However, due to evaporation of contained water and polymerisation of the embedding medium (for Abberior Mount Solid), the refractive index will change over time.
TDE Mounting media are 2,2'-thiodiethanol based embedding media with refractive indices in the range of 1.408 - 1.518. For many applications TDE Mounting media are superior to aqueous embedding media. Especially for demanding applications as 4Pi microscopy, 3D STED microscopy or isoSTED microscopy, because the refractive index will stay constant over time.